By Max Sargent


One thing’s for sure; hybrids keep the cannabis industry interesting. New, unique crosses of old favorites inject novel flavors, scents, and effects into the mix. With so many options available, the hunt to find the perfect hybrid for your setup and preferences can be a daunting one.

Luckily, this list of the top crossbred strains breaks down some of the most diverse and exotic hybrids, with parents from disparate ends of the indica–sativa spectrum or hailing from distant regions of the world. With crossbreeds, old becomes new again!

1. Blue Mystic

Collage showing Blue Mystic cannabis growth stages: seedling, young plant with leaves, budding flower, and mature plant with dense buds.

This strain showcases exactly why experimenting with crossing strains is so important. The lovechild of Blueberry and Northern Light, this cultivar carries genetics from two of the most well loved cannabis strains in the world. The result is a specimen that offers a super strong indica stone alongside fruity berry flavors accented with hints of earth and spice.

Blue Mystic plants tend to grow outwards more than upwards, making for bushy and compact specimens indoors. Here, expect these plants to reach around 25–50 inches; outdoors, Blue Mystic can get quite big, topping out at 85 inches. Generally, we’d recommend giving Blue Mystic around one extra week in veg before flipping it to flowering. Once in bloom, expect it to take around 8 weeks to reach maturity (October harvest outdoors), at which point up to 1.4 oz/ft² indoors and 16 oz/plant outdoors of sweet buds will be yours for the taking!

Blue Mystic
23_genetic background_1 Oregon Blueberry x Northern Light
33_Yield indoors_1 13 to 15 oz/m²
31_plant height outdoor_1 2 to 3 feet
25_flowering time_1 8 - 9 weeks
29_THC_1 THC: 18%
28_Type Blend_1 Sativa 20% Indica 80%
34_yield outdoor_1 14 to 16 oz/plant
32_plant height outdoors_1 6 to 7 feet
27_harvest period_1 October
22_Effect_1 Stoned

Buy Blue Mystic

2. Royal Cheese

Royal Cheese cannabis plant growth stages. Early budding, mature dense buds, and close-up details.

Royal Cheese is not only legendary, but enjoys a “blue blood” reputation in the UK. The smoke she delivers is a sublime mix of sour cheese tastes and stoning effects. This is thanks to formidable parentage in the form of Old School Skunk and Afghan.

This seriously stinky hybrid can reach up to 60 inches indoors, but stretches all the way up to 100 inches when cultivated outdoors. Indoor harvests clock in at around 1.8 oz/ft², whereas she yields up to 21 oz/plant outdoors. Royal Cheese develops flowers seriously fast—you can harvest her in just 7–8 weeks from bloom. That said, if you have a little more patience and love the cheese-like pong, let her mature for up to 10 weeks.

Royal Cheese (Fast Flowering)
23_genetic background_1 Old School Skunk x Afghani
33_Yield indoors_1 16 to 19 oz/m²
31_plant height outdoor_1 2 to 3 feet
25_flowering time_1 7 - 8 weeks
29_THC_1 THC: 17%
28_Type Blend_1 Sativa 40% Indica 60%
34_yield outdoor_1 19 to 21 oz/plant
32_plant height outdoors_1 4 to 7 feet
27_harvest period_1 Early October
22_Effect_1 Balanced, Clear, Stoned

Buy Royal Cheese (Fast Flowering)

3. Cherry Pie

Cherry Pie cannabis plant growth stages: seedling, young plant, flowering plant, and mature plant.

Heralding from Granddaddy Purple (GDP) and Durban Poison, Cherry Pie is about as close to a true indica-sativa hybrid as you can get. Strong, sweet, fast, and generous, this crossbred plant takes the best traits of its two parents and combines them in a single package.

Cherry Pie grows steadily, resulting in a compact canopy that lends itself well to LST. Flip it to flowering in the normal time frame, then watch as a fat canopy of dense buds forms at a maximum height of 47 inches indoors and 70 inches outdoors. On the whole, this strain retains the conical shape of its indica lineage, though it does stretch a little more than some of its indica brethren. Taking 8–9 weeks to finish, you should get a good sense of how big the colas are going to be by around week 5, and then you can sit back and watch as they become ever more resinous. Get ready to haul in up to 1.5 oz/ft² indoors or 17.5 oz/plant outdoors in October.

Cherry Pie
23_genetic background_1 Granddaddy Purple x Durban Poison
33_Yield indoors_1 14 to 16 oz/m²
31_plant height outdoor_1 3 to 4 feet
25_flowering time_1 8 - 9 weeks
29_THC_1 THC: 20%
28_Type Blend_1 Sativa 40% Indica 60%
34_yield outdoor_1 16 to 18 oz/plant
32_plant height outdoors_1 5 to 6 feet
27_harvest period_1 October
22_Effect_1 Balanced, Creative, Euphoric, Uplifting

Buy Cherry Pie

4. Kali Dog

A Kali Dog cannabis plant at various growth stages, from seedling to mature, with dense buds. This strain is known for its citrus flavor and uplifting effects.

Kali Dog is a marijuana cross between Chemdawg and Sour Diesel. Bred around the turn of the century, growers love this strain for its relatively compact stature, dense growth, and generous yields—not to mention its pungent citrus-petrol scent. Kali Dog is not a plant for novice cultivators; but for those with the skill to grow her, she is worth it.

Kali Dog cross bred plants reach medium heights both indoors and out. In the former location, expect specimens to top out at 35–65 inches depending on any training techniques used. Outdoors in full sun, Kali Dog can reach up to 82 inches. The flowering time is a standard 8–10 weeks indoors, at the end of which she yields up to 1.5–1.6 oz/ft². Expect this yield but per plant when grown outdoors, with a harvest time of late October. Kali Dog is also a heavy feeder and loves strong bloom boosters and other nutrients. But for this extra effort you will be rewarded; buds containing 18% THC impart a clear and uplifting high perfect for the daytime.

Kali Dog
23_genetic background_1 Chemdawg x Sour Diesel
33_Yield indoors_1 16 to 19 oz/m²
31_plant height outdoor_1 3 to 5 feet
25_flowering time_1 8 - 10 weeks
29_THC_1 THC: 18%
28_Type Blend_1 Sativa 55% Indica 45%
34_yield outdoor_1 18 to 19 oz/plant
32_plant height outdoors_1 6 to 7 feet
27_harvest period_1 Late October
22_Effect_1 Clear, Uplifting

Buy Kali Dog

5. Bubblegum XL

Bubblegum XL cannabis plant in various growth stages—seedlings, young plants, flowering plants with buds, and mature plants. This hybrid strain is known for its sweet berry flavor and balanced effects.

If you crossed Power Plant and Santa Maria, you wouldn’t necessarily assume the resulting strain would come to be called Bubblegum XL. The history of this cannabis cross begins in Indiana, then travels to New England, before making its way across the Atlantic to the Netherlands where it developed into what we have today. Bubblegum XL features exactly 50% indica and 50% sativa genetics, making for a balanced and enjoyable experience.

As its name suggests, Bubblegum XL exhibits robust growth, quickly developing a strong structure. Once flipped to flowering, the strain takes 8–9 weeks to reach maturity (outdoor harvest in October), reaching final heights of up to 55 inches indoors and 80 inches outdoors. As the grow progresses, fan leaves may take on some purple coloration if nighttime temps are low enough. Some growers like to harvest as early as week 8 of flowering, while others give it another week or even two before raking in up to 1.6 oz/ft² indoors or 16 oz/plant outdoors.

Bubblegum XL
23_genetic background_1 Power Plant x Santa Maria
33_Yield indoors_1 16 to 19 oz/m²
31_plant height outdoor_1 3 to 5 feet
25_flowering time_1 8 - 9 weeks
29_THC_1 THC: 19%
28_Type Blend_1 Sativa 50% Indica 50%
34_yield outdoor_1 14 to 16 oz/plant
32_plant height outdoors_1 5 to 7 feet
27_harvest period_1 October
22_Effect_1 Calming, Uplifting

Buy Bubblegum XL

6. ICE

xplore the growth stages of an ICE cannabis plant: seedling, young plant, flowering plant with buds, and mature plant with dense buds.

This seriously chill cannabis cross between Afghan, Northern Light, and Skunk results in a plant fully covered in resin glands—hence the name! Indeed, the buds produced by this magnificent hybrid are so frosty and sparkly that the moniker is only natural. And best of all, this strain is easy to grow, and fruitful to boot!

Like most heavily indica-dominant strains, ICE (aka Indica Crystal Extreme) is capable of remaining short and stout, reaching only 47 inches indoors. In this setting, she responds well to training and yields up to 1.5 oz/ft² of dense buds after 8–10 weeks of flowering. Outdoors, ICE can stretch up to 80 inches and churn out 17–19.5 oz/plant in late September or early October. Expect a robust body high from this strain, as well as fresh flavor notes of pine and mint.

ICE
23_genetic background_1 Afghan x Northern Light x Skunk
33_Yield indoors_1 14 to 16 oz/m²
31_plant height outdoor_1 3 to 4 feet
25_flowering time_1 8 - 10 weeks
29_THC_1 THC: 18%
28_Type Blend_1 Sativa 10% Indica 90%
34_yield outdoor_1 18 to 19 oz/plant
32_plant height outdoors_1 5 to 7 feet
27_harvest period_1 September
22_Effect_1 Physically Relaxing, Stoned

Buy ICE

7. Trainwreck

A Trainwreck cannabis plant at various growth stages, including seedlings, young plants, flowering plants with buds, and mature plants with dense buds.

This is a three-way marijuana cross that combines the power of some fantastic landraces: Mexican x Thai x Afghan! Each of these wild specimens brings something distinct and important, not just to this strain, but to the world of cannabis in general. Regarding Trainwreck, the result of this cross is a 90% sativa plant with a fantastic terpene profile, invigorating effects, and robust growth.

As Trainwreck mostly contains sativa genetics, it requires a little more care compared to indica-dominant varieties. What’s more, it grows a little taller than many plants, reaching around 60 inches indoors and 80+ inches outdoors. However, it flowers relatively quickly, in only 9–10 weeks (late October harvest outdoors). As such, it’s a great option for impatient growers who want to try their hand at a sativa. This strain tends to shoot up quite fast, and once it starts to flower, it can double in size during the first week! Prepare for ample yields of up to 2 oz/ft² indoors or 25 oz/plant outdoors.

Trainwreck
23_genetic background_1 Mexican x Thai x Afghan
33_Yield indoors_1 19 to 21 oz/m²
31_plant height outdoor_1 3 to 5 feet
25_flowering time_1 9 - 10 weeks
29_THC_1 THC: 19%
28_Type Blend_1 Sativa 90% Indica 10%
34_yield outdoor_1 23 to 25 oz/plant
32_plant height outdoors_1 5 to 7 feet
27_harvest period_1 Late October
22_Effect_1 Creative, Euphoric, Uplifting

Buy Trainwreck

8. Royal AK

A Royal AK cannabis plant at various growth stages: seedling, young plant, flowering plant with buds, and mature plant.

Royal AK is a shotgun blast of a crossbred strain, delivering an incredibly pure and uplifting high. This 18% THC powerhouse is the result of Colombian, Mexican, Thai, and Afghan landraces, resulting in a 60% sativa and 40% indica mix. The plant has an exceptionally strong scent as well, bearing tantalizing notes of berries, fruit, and diesel.

Indoors, Royal AK usually reaches between 31–55 inches in height, yielding 1.7–1.9 oz/ft² after 8–9 weeks of flowering. Outdoors, she can stretch to as much as 67 inches and produce between 21–23 oz/plant in mid-October. Despite being sativa dominant, Royal AK keeps the wait relatively short while retaining a sativa-like morphology and uplifting terpenes. For indoor growers looking to cultivate this specimen, consider using the ScrOG technique to maximize production and keep plant height to a minimum.

Royal AK
23_genetic background_1 Columbian, Mexican, Thai & Afghan
33_Yield indoors_1 18 to 20 oz/m²
31_plant height outdoor_1 3 to 5 feet
25_flowering time_1 8 - 9 weeks
29_THC_1 THC: 19%
28_Type Blend_1 Sativa 60% Indica 40%
34_yield outdoor_1 21 to 23 oz/plant
32_plant height outdoors_1 4 to 6 feet
27_harvest period_1 Early October
22_Effect_1 Balanced, Clear, Stoned

Buy Royal AK

9. Dynamite Diesel | Tyson 2.0

Dynamite Diesel cannabis plant at different growth stages: a close-up of a bud, a flowering plant with forming buds, a mature plant with dense buds, and another close-up of a bud

Dynamite Diesel is part of our collaboration with Mike Tyson, where we bring his favorite cross breed marijuana strains to market as stable seeds. The progeny of Sour Diesel and Skywalker OG, this strain is mostly indica but contains around one-third sativa genetics, which prevents it from being too heavy regarding its stoning effects.

Requiring 9–10 weeks to flower, or a long summer outdoors, it’s not the fastest strain in the world but it is well worth the effort. It grows well, producing large canopies with many bountiful bud sites, and thanks to its robust nature, it takes well to training. During the vegetative stage it will grow to around 40 inches or so in height. And then, depending on where it’s growing and whether you’ve used any training methods, it can reach a maximum of 60 inches indoors or 80 inches outdoors. Prepare to support the branches in the final weeks of flowering, as it can produce up to 1.8 oz/ft² indoors or 24 oz/plant outdoors.

Dynamite Diesel
23_genetic background_1 Sour Diesel x Skywalker OG
33_Yield indoors_1 18 to 19 oz/m²
31_plant height outdoor_1 3 to 5 feet
25_flowering time_1 9 - 10 weeks
29_THC_1 THC: 22%
28_Type Blend_1 Sativa 35% Indica 65%
34_yield outdoor_1 22 to 24 oz/plant
32_plant height outdoors_1 5 to 7 feet
27_harvest period_1 October
22_Effect_1 Calming, Physically Relaxing, Sleepy, Uplifting

Buy Dynamite Diesel

10. Fruit Spirit

Fruit Spirit cannabis plant at different growth stages: seedling, young plant, flowering plant with buds, and mature plant with dense buds.

Fruit Spirit results from a cross between Blueberry and White Widow, birthing one of the sweetest strains on the market today. The smoke Fruit Spirit delivers is outstanding. Alongside an 18% THC content, she also has a super-sweet blueberry taste.

This indica-dominant (70%) strain seldom reaches 40 inches when grown indoors. That said, she can still produce up to 1.4 oz/ft² after 9–10 weeks under powerful lights. Outside in a sunny environment, she can top out at 80 inches and deliver up to 18.5 oz/plant come mid-October. This is a great strain for growing in warm and tropical environments like Spain, Italy, Greece, Jamaica, and Brazil. In order to retain the characteristic flavor of this strain to its fullest, consider dry trimming your plants instead of wet trimming.

Fruit Spirit
23_genetic background_1 Blueberry x White Widow
33_Yield indoors_1 13 to 15 oz/m²
31_plant height outdoor_1 3 to 4 feet
25_flowering time_1 9 - 10 weeks
29_THC_1 THC: 18%
28_Type Blend_1 Sativa 30% Indica 70%
34_yield outdoor_1 17 to 18 oz/plant
32_plant height outdoors_1 6 to 7 feet
27_harvest period_1 Early October
22_Effect_1 Clear

Buy Fruit Spirit

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